Playing with any enabled mod (unless Mom has been beaten).During a Daily Challenge, although the achievement associated with this game mode are unaffected.During a Challenge, although the achievement for completing the challenge is unaffected.Certain cosmetic and difficulty-increasing special seeds will still allow unlocks. Conditions which can disable the ability to unlock achievements include: If Isaac is unable to unlock achievements, a small icon of a crossed-out trophy will be displayed below the Key's counter. In the PC version, every Steam achievement exactly corresponds to one secret in-game, whereas only a handful of secrets are represented by PSN trophies in the PlayStation version of the game. For tips and strategies on completing achievements, see achievement tips.Īchievements are unlocked after completing Challenges, reaching certain milestones, achieving hidden goals, or unlocking certain items.